type 2 diabetes
Conditions
Interventions
Hospitalized patients with type 2 diabetes under Basal-Bolus insulin therapy with glargine will be enrolled. First CGMS for 72-h will be performed after fasting blood glucose are controlled to the ran
Sponsors
Naga Municipal Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients with type 2 diabetes who meet the following conditions: (1)Age: younger than 75 years old, elder than 20 years old (2)recent HbA1c : less than 12.0%
Exclusion criteria
Exclusion criteria: Patients who falls under any of the following conditions shall be excluded: (1)diabetic coma (2)severe renal dysfunction (eGFR less than 30) (3)unstable pre or proliferative diabetic retinopathy (4)severe infection (5)administered steroid drugs (6)pregnant or planned pregnant in the near future (7)ineligible for some other medical reasons judged by the investigator
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Comparison of glucose variability between two treatments by the Continuous Glucose Monitoring System (Frequency of nocturnal hypoglycemia by basal-bolus insulin treatment with glarugine and degludec) | — |
Secondary
| Measure | Time frame |
|---|---|
| 1)Standard deviation of nocturnal blood glucose levels 2)Correlation between ability of insulin secretion and Bolus/ Basal insulin ratio 3)Correlation between ability of insulin secretion and the frequency of nocturnal hypoglycemia | — |
Countries
Japan
Contacts
Public ContactTetsushi Nasu
Naga Municipal Hospital Department of Internal Medicine
Outcome results
None listed