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Effect of rebamipide on anemia in patients under LDA or NSAIDs treatment -exploratory research-

Effect of rebamipide on anemia in patients under LDA or NSAIDs treatment -exploratory research- - Effect of rebamipide on anemia in patients under LDA or NSAIDs treatment

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000010499
Enrollment
30
Registered
2013-05-07
Start date
2013-05-07
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

anemia induced by ulcers and /or erosions of small intestine

Interventions

rebamipide 900mg/day

Sponsors

Dept of Gastroenterology and Metabolism, Nagoya City University Graduate School of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Age: more than 20 years old. Regardless of sex. 2. Patients who were diagnosed as iron deficiency anemia and /or occult blood test of feces positive 3. Patients whose LDAs and/or NSAIDs and/or other anti-platelet agents doses were not changed in 3 months before informed consent acquisition. 4. Patients who were not detected any lesions speculated to be the cause of anemia in GIF and CF examination in 3 months before informed consent acquisition. 5. Patient whose informed consent was obtained in the documents.

Exclusion criteria

Exclusion criteria: 1.Patients who were detected some bleeding lesions in GI tract. 2.Patients who were diagnosed as GI tract obstraction. 3.Patients with malignant neoplasia 4.Patients who were detected any tumors and /or diverticula as the origin of bleeding in small intestine. 5.Patients who were speculated to have bleeding from the diverticulum of colon. 6.Patinets of Crohn' s disease and/or UC. 7.Patients who were speculated to the bleeding from anywhere but GI tract. 8.Patient who received surgical operation in 3 months before study. 9.Patients whose medication were changed. 10.Patients who undergo dialysis. 11.Patients who have renal disturbance; serum creatinine, Scr>2 mg/dL. 12. Patients who need erythropoietin administration 13. Patients who were speculated to be iron uptake disturbance after gastrectomy 14. Patients who are decompensated liver cirrhosis 15. Patients who take sulfasalazine and/or misoprostole and/or antibiotics 16. Patients who are judged to be inappropriate for this clinical trial by attending physician.

Design outcomes

Primary

MeasureTime frame
changes of hemoglobin by rebamipide treatment

Countries

Japan

Contacts

Public ContactKataoka H, Kubota E

Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan Dept of Gastroenterology and Metabolism

hkataoka@med.nagoya-cu.ac.jp052-853-8211

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026