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Slow injection of nefopam reduces pain intensity associated with intravenous injection: A clinical trial

Slow injection of nefopam reduces pain intensity associated with intravenous injection: A clinical trial - Slow injection of nefopam reduces injection pain

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000010484
Enrollment
102
Registered
2013-04-13
Start date
2013-04-13
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

elective minor surgery

Interventions

The i.v. solution (30 mg of nefopam is diluted with 0.9% isotonic saline to a total volume of 20 mL) is administered at a rate of 60 mL/h The i.v. solution (30 mg of nefopam is diluted with 0.9% isot

Sponsors

Korea University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients aged 20~65 years with a physical status of 1 (the American Society of Anesthesiologists rating) who are scheduled to undergo elective minor surgery

Exclusion criteria

Exclusion criteria: Patients with a history of cardiovascular, kidney, or liver disease, those with a current convulsive disorder or hypersensitivity to drugs, and those receiving any analgesics; Patients with a vein that do not drain well; those with redness, swelling, and tenderness along the veins; and those with a history of difficult peripheral venous cannulation.

Design outcomes

Primary

MeasureTime frame
Visual analogue pain scale at intravenous injection of nefopam

Secondary

MeasureTime frame
Adverse effects including phlebitis caused by nefopam injection

Countries

Asia(except Japan)

Contacts

Public ContactByung Gun Lim

Guro Hospital, Korea University College of Medicine Department of Anesthesiology and Pain Medicine

bglim9205@korea.ac.kr82-2-2626-1437

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026