Type 2 diabetes mellitus
Conditions
Interventions
degludec 4units/day and Quick insulin 4units every meals,then doses of insulin is adjusted according to the algorythm.
Glargine 4units/day
Sponsors
Yokohama City University Medical Center
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1)before test registration - no insulin therapy and inpatient 2)FPG :more than 200mg/dl, PPG:more than 300mg/dl 3)HbA1c :more than 8.0%, less than 14% 4)Type 2 diabetes 5)Age more than 20, less than 85Type 6)Pts with written IC
Exclusion criteria
Exclusion criteria: 1)severe ketosis, diabetic coma within 6 months 2)severe infection, before operation, severe trauma 3)severe hepatic dysfunction 4)or severe renal dysfunction (SCr:more than 2.0mg/dl or eGFR less than 30) 5)pregnacy 6)Allergy for glargine and degludec 7)Patients judged by the investigator to be ineligible for some other reason
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Achievement rate of FPG <110mg/dl and PPG <180mg/dl after treatment with glargine or degludec | — |
Secondary
| Measure | Time frame |
|---|---|
| 1)Glucose variability, CV. 2)Achievment rate of <110mg/dl of FPG or 180mg/dl of PPG 3)FPG and PPG after 2 weeks of treatment 4)days to achieve target 5)frequencies of hypoglycemia 6)Achievment rate of <130mg/dl of FPG or 200mg/dl of PPG 7)lipid control 8)MAGE and CV in CGM | — |
Countries
Japan
Contacts
Public ContactJun Suzuki
Yokohama City University Medical Center Department of Endocrinology and Diabetes
Outcome results
None listed