Microbiological effect of a 3-step care (brushing, flossing, gargling) on oral cavity niches in chronic periodontitis patients: : a randomized controlled clinical trial

Microbiological effect of a 3-step care (brushing, flossing, gargling) on oral cavity niches in chronic periodontitis patients: : a randomized controlled clinical trial - Microbiological effect of a 3-step care in periodontitis patients

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000010444

Enrollment

Registered

2013-04-09

Start date

2009-12-10

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Moderate to severe chronic periodontitis

Interventions

Test group 1. 20 patients 2. Subjects continuously undergo a 3- step care regimen (brushing, flossing, gargling) for 4 weeks. Control group 1. 20 patients 2. Subjects continuously undergo

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Moderate to severe chronic periodontitis patients 2. Possessed a minimum of 20 teeth 3. Having at least 3 teeth with probing pocket depth greater than 4 mm in each quadrant.

Exclusion criteria

Exclusion criteria: 1.Persons who had received periodontal treatment within the previous 6 months 2. Persons who had taken systemic antibiotics, anti-inflammatory drugs, or immunosuppressive drugs within 3 months 3. Persons who were regularly using a tongue cleaner and mouth rinse

Design outcomes

Primary

Measure	Time frame
Bacterial counts from tonsils, tongue coating and subgingival plaque	—

Secondary

Measure	Time frame
Volatile sulfur compound levels	—

Countries

Japan

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026