Influence of preoperative vitamin C administration on suppresive effect of oxidative stress in patients with colorectal cancere receiving parenteral nutrition

Influence of preoperative vitamin C administration on suppresive effect of oxidative stress in patients with colorectal cancere receiving parenteral nutrition - Influence of preoperative vitamin C administration on suppresive effect of oxidative stress in patients with colorectal cancere receiving parenteral nutrition

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000010400

Enrollment

Registered

2013-04-02

Start date

2013-04-02

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients with colorectal cancer who need preoperativ parenteral nutrition

Interventions

Patietns with administration of preoperative Vit C. Patietns without administration of preoperative Vit C.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1: Patients with more than 20 years old. 2: Patients who can get an informed consent from themselves.

Exclusion criteria

Exclusion criteria: 1: Patients with uncontrollable diabetes (blood sugar >= 200mg/dL or urinary ketone positive). 2: Patients with liver dysfunction (The serum levels of AST >=120 IU/L or ALT >=100 IU/L). 3: Patients with renal failure (The serum levels of Cre >= 2mg/dL or BUN >= 40 mg/dL). 4: Patients with congenital abnoramilty of aminoacid metaobolism. 5: Patients with allergy for Vit C. 6: Patients with hemophilia.

Design outcomes

Primary

Measure	Time frame
To estimate the suppresive effect for preoperative administration of vitamin C for patietns with colorectal cancera undergoing surgery.	—

Countries

Japan

Contacts

Public ContactMitsuru Ishizuka

Dokkyo Medical University Department of Gastroenterological Surgery

mm-ishizuka@umin.ac.jp0282-87-2158

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026