Evaluation of the effectiveness of the preoperative administration of a single-dose preparationof azithromycin, in chest surgery.

Evaluation of the effectiveness of the preoperative administration of a single-dose preparationof azithromycin, in chest surgery. - Evaluation of the preoperative administration of a single-dose preparationof azithromycin.

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000010368

Enrollment

Registered

2013-04-01

Start date

2013-04-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

primary lung cancer

Interventions

preoperative administration of a single-dose preparation of azithromycin

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients who are planned to be performed surgery for primary lung cancer in our center

Exclusion criteria

Exclusion criteria: (1) patient with hypersensitivity to azithromycin or macrolide derivative antimicrobials (2)patinet with congenital long QT, bradycardia, arrhythmia, heart failure or electrolyte disorders such as hyperkalemia and hypomagnesemia, or patient receiving long QT-inducible drugs such as class IA or III antiarrhythmic, psychotropic and antidepressant (3)patient with severe liver dysfunction(Child Pugh C) (4)patient of aherediatry fructose intolerance symptom, glucose galactose absoroption imperfecton or sucrose isomaltase deficiency (5)patient recieving other antimicrobials (6)A pregnant woman or the patient who is nursing (7)the patient who is judged to be inappropriate by the examination medical attendant

Design outcomes

Primary

Measure	Time frame
perioperative infection prophylaxis in lung cancer surgery.	—

Secondary

Measure	Time frame
concentration of azithromycin in lung, microbiological examination in lung, inflammatory cytokines expression.	—

Countries

Japan

Contacts

Public ContactHironosuke Watanabe

Nagasaki University Hospital Surgical Oncology

hironosuke3689@yahoo.co.jp095-819-7304

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026