The efficacy of pilocarpine for xerostomia induced by radiation therapy at different administration timing.

The efficacy of pilocarpine for xerostomia induced by radiation therapy at different administration timing. - The efficacy of pilocarpine for xerostomia induced by radiation therapy at different administration timing.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000010288

Enrollment

Registered

2013-04-01

Start date

2013-05-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

xerostomia

Interventions

To compare the efficacy of pilocarpine for xerostomia at different administration timing, during and after radiation therapy for head and neck cancer patients.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Patients received radiation therapy for epipharynx, oropharynx and pharynx. 2. Written informed consent obtained before begingingany investigational procedures.

Exclusion criteria

Exclusion criteria: 1. Patients who have contraindication to pilocarpine. 2. Pregnant women or patients who have possibility of pregnancy. 3. Patients the principal investigator deems unsuitable as a subject.

Design outcomes

Primary

Measure	Time frame
a visual analog scale xerostomia questionnaire quantity of secreted saliva	—

Secondary

Measure	Time frame
Oral findings	—

Countries

Japan

Contacts

Public ContactMariko Moriya

Kawasaki Medical School Otorhinolaryngology

moriya@med.kawasaki-m.ac.jp086-462-1111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026