Safety and efficacy of transplantation of tissue-engineered autologous oral mucosal epithelial cell sheets in preventing formation of strictures after endoscopic submucosal dissection for esophageal cancer

Safety and efficacy of transplantation of tissue-engineered autologous oral mucosal epithelial cell sheets in preventing formation of strictures after endoscopic submucosal dissection for esophageal cancer - Safety and efficacy of transplantation of oral mucosal epithelial cell sheets in preventing formation of strictures after ESD

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000010251

Enrollment

Registered

2013-04-01

Start date

2013-04-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

superficial esophageal cancer

Interventions

We transplant tissue-engineered autologous oral mucosal epithelial cell sheets to ulcer surface after endoscopic submucosal dissection for esophageal cancer

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients with large esophageal cancer expected to result in a post-ESD artificial ulcer of a size of not less than two-thirds of the circumference

Exclusion criteria

Exclusion criteria: Exclusion criteria includes severe diabetes mellitus, heart disease, renal desease, active double cancers, undergoing treatment for oral, laryngeal, pharyngeal cancers, receiving radiotherapy for early esophageal cancer

Design outcomes

Primary

Measure	Time frame
Intra and post-operative morbidity, stricture, dysphagia score	—

Countries

Japan

Contacts

Public ContactKengo Kanetaka

Nagasaki University Hospital Department of Surgery

kanetaka@nagasaki-u.ac.jp095-819-7316

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026