Comparison of additive effect of omega-3 fatty acid or ezetimibe in combination with statins on the reduction of small dense LDL in patients with coronary artery disease

Comparison of additive effect of omega-3 fatty acid or ezetimibe in combination with statins on the reduction of small dense LDL in patients with coronary artery disease - Comparison of additive effect of omega-3 fatty acid or ezetimibe in combination with statins on the reduction of small dense LDL in patients with coronary artery disease

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000010242

Enrollment

Registered

2013-03-15

Start date

2013-03-15

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Uncontrolled dyslipiemic patients with coronary artery disease under statin use

Interventions

Omega-3 fatty Ezetimib

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1)adults over 20 years old 2)HbA1c less than 9% 3)Change in HbA1c plus/minus 1% during last 3 months

Exclusion criteria

Exclusion criteria: 1)TG>=400mg/dL 2)Patients receiving insulin therapy 3)Pregnant woman or possibly pregnant woman 4)Patients having allergy for study drug 5)Active hepatitis or liver cirrhosis 6)Serum creatinine >2mg/dL 7)Patients suffered from acute coronary syndrome or stroke last 3 months 8)Secondary hyperlipidemia, drug-induced hyperlipidemia, familial hyperlipidemia

Design outcomes

Primary

Measure	Time frame
Change in small dense LDL	—

Countries

Japan

Contacts

Public ContactToru Miyoshi

Okayama University Graduate School of. Medicine, Dentistry and Pharmaceutical Sciences Cardiovascular Medicine

miyoshit@cc.okayama-u.ac.jp086-235-7351

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026