Estimation of platelet-rich fibrin on prevention of bisphosphonate-related osteonecrosis of the jaw

Estimation of platelet-rich fibrin on prevention of bisphosphonate-related osteonecrosis of the jaw - Estimation of platelet-rich fibrin on prevention of bisphosphonate-related osteonecrosis of the jaw

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000010239

Enrollment

Registered

2013-04-01

Start date

2013-04-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

bisphosphonate-related osteonecrosis of the jaw

Interventions

A total of 10 subjects,3 months study. a patientreceiving oral bisphosphonate therapy for not less than 1 year. platelet-fibrin is separated from blood and plugged into extraction socket.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: a patient receiving oral bisphosphonate therapy for not less than 1 year. a patient who needs to extract teeth

Exclusion criteria

Exclusion criteria: poor general condition a patients who is difficult to visit our hospital for 3 months after tooth extraction.

Design outcomes

Primary

Measure	Time frame
percentage of the cases without impaired healing of socket The incidence of adverse event	—

Countries

Japan

Contacts

Public ContactTakuya Asaka

Hokkaido University Graduate School of Dental Medicine

asakatakuya@den.hokudai.ac.jp011-706-4280

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026