Classification of subsets of psoriasis based on expression profile of cytokines in lesional skin of psoriasis

Classification of subsets of psoriasis based on expression profile of cytokines in lesional skin of psoriasis - Cytokines in lesional skin of psoriasis

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000010225

Enrollment

Registered

2013-04-30

Start date

2013-04-30

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

psoriasis

Interventions

Biopsy of lesional skin of patients with psoriasis is done with local anaesthesia 1. 3mm punch biopsy 2. once at the first visit 3. in case of necessity at the recurrence

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients with moderate and severe psoriasis

Exclusion criteria

Exclusion criteria: 1.Patients with severe infection 2.Patients with active tuberculosis 3.Carrier of hepatitis B virus

Design outcomes

Primary

Measure	Time frame
Quantification TNFa, IL17A, IL12/23p40 mRNA expression in lesional skin of patients with psoriasis at their first visit and the recurrence.	—

Secondary

Measure	Time frame
Ratio of TIP-DC/Th17/Th22 cells and FoxP3+Treg cells in lesional skin of patients with psoriasis at their first visit and the recurrence.	—

Countries

Japan

Contacts

Public ContactFujimoto Wataru

Kawasaki Medical School Department of Dermatology

watarufu@med.kawasaki-m.ac.jp086-462-1111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026