Implication of central blood pressure and renal arterio-arteriolosclerosis in chronic kidney disease (CKD) patients

Implication of central blood pressure and renal arterio-arteriolosclerosis in chronic kidney disease (CKD) patients - Central blood pressure and renal arterio-arteriolosclerosis

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000010214

Enrollment

100

Registered

2013-04-01

Start date

2013-04-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic kidney disease

Interventions

Measurement of central blood pressure

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) CKD patients who are planning to receive the renal biopsy 2) Patients with the informed consent to this study

Exclusion criteria

Exclusion criteria: 1) Acute renal failure 2) Acute glomerulonephritis or rapidly progressive glomerulonephritis 3) Patients with inflammatory or consumptive diseases (e.g. infection, malignant tumor, vasculitis, collagen disease)

Design outcomes

Primary

Measure	Time frame
Relation between central systolic blood pressure and renal arterio-arteriolosclerosis	—

Secondary

Measure	Time frame
Relation between central systolic blood pressure and clinical indexes below 1) Renal histopathologic indexes (glomerulosclerosis, interstitial fibrosis/tubular atrophy, interstitial cell infiltration) 2) Cardio-ankle vascular index (CAVI) 3) Resistive index (RI) using the kidney doppler ultrasonography 4) Urinary parameters (albumin, N-acetyl-beta-glucosaminidase, beta2-microgloburin) 5) Renal function (estimated glomerular rate by creatinine and cystatin C)	—

Measure

Time frame

Relation between central systolic blood pressure and clinical indexes below 1) Renal histopathologic indexes (glomerulosclerosis, interstitial fibrosis/tubular atrophy, interstitial cell infiltration) 2) Cardio-ankle vascular index (CAVI) 3) Resistive index (RI) using the kidney doppler ultrasonography 4) Urinary parameters (albumin, N-acetyl-beta-glucosaminidase, beta2-microgloburin) 5) Renal function (estimated glomerular rate by creatinine and cystatin C)

—

Countries

Japan

Contacts

Public ContactTamehachi Namikoshi

Kawasaki Medical School Department of Nephrology and Hypertension

tnamikoshi@med.kawasaki-m.ac.jp086-462-1111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026