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Double-blind, randomized, controlled trial of the effects of probiotics for chemotherapy-induced gastrointestinal mucositis

Double-blind, randomized, controlled trial of the effects of probiotics for chemotherapy-induced gastrointestinal mucositis - Study the effectiveness of probiotics for chemotherapy-induced gastrointestinal mucositis

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000010203
Enrollment
40
Registered
2013-03-12
Start date
2013-04-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Multiple Myeloma

Interventions

B.breve administered orally three times a day. Continued until three weeks after the start of the chemotherapy two weeks before the start of chemotherapy. Collected blood and stool at 2 weeks before

Sponsors

Department of Hematology. Juntendo University School of medicine.
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Adult patients admitted to the hospital for treatment with auto-PBSCT in order to be diagnosed with multiple myeloma in Department of Hematology Juntendo University School of medicine.

Exclusion criteria

Exclusion criteria: 1.Patient who has a colostomy and gastrostomy. 2.Patient being treated has a collagen disease such as immune dysfunction. 3.Patient being treated has a cranial nerve dysfunction or heart failure during treatment. 4.Patients with more than two weeks, the oral administration of probiotics before the start of this clinical research. 5.Patients not undergoing cryotherapy 6.If the the attending physician has determined inappropriate to participate in this study.

Design outcomes

Primary

MeasureTime frame
bacterial rRNA-targeted reverse transcription-quantitative PCR(BrRNA RT-PCR)

Countries

Japan

Contacts

Public ContactSakurai Hiroko

Juntendo University School of medicine. Department of Hematology.

hiiduka@juntendo.ac.jp03-5802-1069

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026