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Compare efficacy and safety of alpha1-blockers in patients with benign prostatic hyperplasia

Compare efficacy and safety of alpha1-blockers in patients with benign prostatic hyperplasia - Compare the treatment of the alpha1-blockers

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000010198
Enrollment
70
Registered
2013-03-11
Start date
2012-02-12
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Benign Prostatic Hyperplasia

Interventions

Tamusulosin 8 weeks 0.2 mg once a day Naftopidil 8 weeks 75 mg once a day

Sponsors

Matsushita Urologocal Clinic
Lead Sponsor

Eligibility

Sex/Gender
Male

Inclusion criteria

Inclusion criteria: 1)The patients aged more than 50 years who written informed consent was obtained . 2)The patients who had a diagnosis of bengin prostatic hyperplasia with non-treatment. 3)I-PSS total score higher than 8 and QOL score higher than 2

Exclusion criteria

Exclusion criteria: 1)Patients who have taken a medicine that influence on the urination function. 2)Patients with suspected prostate cancer. 3)Patients with suspected Neurogenic Bladder. 4)Patients with urethral stricture. 5)Patients who gave radiotherapy in the pelvis. 6)Patients with urinary tract infection, calculus urinary, cystitis interstitial. 7)Patients with serious impaired liver function, serious renal dysfunction, serious heart disorder. 8)Patients with orthostatic hypotension. 9)Patients with myasthenia gravis. 10)Maximum urinary flow rate=>15mL/s 11)The inappropriate patients who is judged by urologist.

Design outcomes

Primary

MeasureTime frame
International Prostate Symptom Score BPH Impact Index

Secondary

MeasureTime frame
Blood Pressure

Countries

Japan

Contacts

Public ContactMasami Matsushita

Matsushita Urologocal Clinic Department of Urology

kzkk77731@leto.eonet.ne.jp0795-73-0266

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026