Inhibitory effect of cardiac resynchronization therapy on sympathetic nerve activity in chronic heart failure patients

Inhibitory effect of cardiac resynchronization therapy on sympathetic nerve activity in chronic heart failure patients - Inhibitory effect of cardiac resynchronization therapy on sympathetic nerve activity in chronic heart failure patients

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000010119

Enrollment

Registered

2013-03-01

Start date

2013-03-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic heart failure

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Twenty consecutive patients with advanced heart failure who meet clinical criteria for a CRT implantation ( LVEF<35%, NYHA function class 3 or 4, QRS durationz>120ms and optimal medical therapy).

Exclusion criteria

Exclusion criteria: Patints with recent myocardial infarction, cardiac surgery(<3 months), unstable medical conition, and chronic atrial fibrillation are excluded.

Design outcomes

Primary

Measure	Time frame
Effect of cardiac resynchronization therapy on muscle sympathetic nerve activity, 24 and 48 week after implantation.	—

Countries

Japan

Outcome results