Advanced endothelial dysfunction in patients with coexistence of coronary artery disease and peripheral arterial disease - effects of Cilostazol on endothelial dysfunction in peripheral arterial disease -

Advanced endothelial dysfunction in patients with coexistence of coronary artery disease and peripheral arterial disease - effects of Cilostazol on endothelial dysfunction in peripheral arterial disease - - Examination concerning the endothelial function of the patients with coexistence of coronary artery disease and peripheral arterial disease

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000010106

Enrollment

Registered

2013-02-25

Start date

2006-08-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

The cases with coexistence of coronary artery disease and peripheral arterial disease

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: The coronary artery disease (CAD) patient who has a peripheral artery disease (PAD). PAD (1)ABI < 0.9 (2)Fontaine classification >= II (3) previous revascularization in lower limbs (4) occlusive arteries in lower limbs by imaging examinations CAD as the presence of >= 50% narrowing of coronary artery diameter in at least one major coronary artery

Exclusion criteria

Exclusion criteria: (1)heart failure with reduced left ventricular systolic function (ejection fraction<50%) (2)severe valvular heart disease(3)cardiomyopathy (4)systemic illness [including advanced endocrine, hepatic, or renal diseases (5)active inflammatory diseases (6)cancer (7)with residual hemiplegia

Design outcomes

Primary

Measure	Time frame
endothelial evaluation of function by reactive hyperemia peripheral arterial tonometry	—

Secondary

Measure	Time frame
The effect of Cilostazol to the peripheral artery disease patients	—

Countries

Japan

Outcome results