Evaluation of host QOL and immune function in breast cancer patients with combination of adjuvant chemotherapy and oral administration of Lentinula edodes mycelia extract.

Evaluation of host QOL and immune function in breast cancer patients with combination of adjuvant chemotherapy and oral administration of Lentinula edodes mycelia extract. - Evaluation of host QOL and immune function in breast cancer patients with combination of adjuvant chemotherapy and oral administration of Lentinula edodes mycelia extract.

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000010047

Enrollment

Registered

2013-02-14

Start date

2011-01-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

breast cancer

Interventions

1)Curative resection of breast cancer. 2)Adjuvant chemotherapy with FAC, FEC, AC or EC. 1)Curative resection of breast cancer. 2)Adjuvant chemotherapy with FAC, FEC, AC or EC combined with LEM.

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: 1)Histologically proven breast cancer. 2)4) Adequate organ functions: WBC >=3500/mm3 and <=12000/mm3, platelets >=100,000/mm3, hemoglobin >=8.0g/dL, total bilirubin <=1.5mg/dL, AST(GOT)/ALT(GPT) <=2.5 X UL, creatinine <=UL. 3)ECOG Performance status:0-2. 4)Expected survival over 3 months. 5)Age of 20 years or older. 6)female 7)Written informed consent

Exclusion criteria

Exclusion criteria: 1)Pregnant females, possibly pregnant females, females wishing to become pregnant. 2)Nursing mothers. 3)Prior radiotherapy, chemotherapy or hormone therapy. 4)Other patients who are unfit for the study as determined by the attending physician.

Design outcomes

Primary

Measure	Time frame
QOL(FACT-BRM)	—

Countries

Japan

Contacts

Public ContactShigefumi Yoshino

Yamaguchi University Graduate School of Medicine Department of Digestive Surgery and Surgical Oncology

sigefumi@yamaguchi-u.ac.jp0836-22-2264

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026