colorectal cancer
Conditions
Interventions
1)Curative resection 2)UFT (Stage II) or UFT/LV (Stage III) for 1 year
1)Curative resection 2)UFT (Stage II) or UFT/LV (Stage III) combined with PSK for 1 year
Sponsors
Department of Digestive Surgery and Surgical Oncology, Yamaguchi University Graduate School of Medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1)Histologically proven adenocarcinoma of colon cancer. 2)Patients with Stage II, III and recieved curative resection. 3)No prior radiotherapy, chemotherapy. 4)Age of 20 years or older, 79 years or younger. 5)ECOG Performance status:0-2. 6)Adequate organ functions: without watery diarrhea WBC >=3000/mm3, platelets >=100,000/mm3, AST(GOT)/ALT(GPT) <=100IU/L, total bilirubin <=2.0mg/dL, creatinine <=UNL. 7)Written informed consent.
Exclusion criteria
Exclusion criteria: 1)Patients with non-curative resection. 2)Patients with anal canal cancer. 3)Patients with GI stricture. 4)A large amount of pleural effusion or peritoneal fluid. 5)Infection 6)Active synchronous malignancy. 7)Pregnant females, possibly pregnant females, females wishing to become pregnant and nursing mothers. 8)Severe complications, such as uncontrolled diabetes mellitus. 9)Severe complications, such as heart failure. 10)Severe mental disorders. 11)Patients under treatment with steroid. 12)Other patients who are unfit for the study as determined by the attending physician.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 3 years disease free survival | — |
Countries
Japan
Contacts
Public ContactShigefumi Yoshino
Yamaguchi University Graduate School of Medicine Department of Digestive Surgery and Surgical Oncology
Outcome results
None listed