Atopic dermatitis
Conditions
Interventions
Applying Split-plot design, multiple factors are randomized. 4 sites of each cubital fossa and popliteal fossa are used as a independent site respectively. 1st factor is presence or absence of filagg
Sponsors
Hokkaido University Graduate School of Medicine, Department of Dermatology
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients of atopic dermatitis diagnosed by the diagnostic criteria for atopic dermatitis by Hanifin & Rajika, U.K.Working Party or Japan Society of Dermatology. Patients with moderate to severe skin lesions.
Exclusion criteria
Exclusion criteria: Patients who have obviously infected lesion in the popliteal and cubital fossa. Patients who have atrophy or telangiectasia in the popliteal and cubital skin caused by the topical steroid application. Patients who has serious underlying disease. Patients who had participated in other clinical trials within 6 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Amount of change in the score of intensity which is used in SCORAD. 6 criteria include erythema, edema/ papulation, oozing/ crusting, excoriation and lichenification which is scored by 0 to 3 points respectively. | — |
Secondary
| Measure | Time frame |
|---|---|
| TEWL SC hydration VAS of itch Evaluation of presence or absence of flare-ups in the sites which are/ are not apllied moisturizer for the sites without eruption. | — |
Countries
Japan
Contacts
Public ContactOsamu Mizuno
Hokkaido University Hospital Department of Dermatology
Outcome results
None listed