MRI Measurement of Lead Location for Suboptimal Outcomes after Deep Brain Stimulation

MRI Measurement of Lead Location for Suboptimal Outcomes after Deep Brain Stimulation - MRI trouble shooting for DBS study (MRI-DBS study)

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000009996

Enrollment

Registered

2013-02-27

Start date

2013-02-04

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Parkinson&#39

Interventions

MRI

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Include either 1 or 2: 1. Patients with suboptimal clinical efficacy after DBS therapy. 2. Patients who cannot increase DBS settings due to stimulation induced side effects.

Exclusion criteria

Exclusion criteria: Exclusion criteria are following. 1. Pregnant women and, nursing mothers 2. Patients who have cardiac pacemaker. 3. Patients who cannot understand the concept of this study or who cannot obtain written consent. 4. Patients who are assumed not to be appropriate candidate for this study by investigators.

Design outcomes

Primary

Measure	Time frame
The Parkinson's Disease Questionnaire (PDQ-39)	—

Secondary

Measure	Time frame
1.Unified Parkinoson's Disease Rating Scale (UPDRS) part I, II, IV 2.UPDRS-III (on/off stimulation, on/off medication) 3. Impedance 4.threshoulds for efficacy and side effect of DBS 5. Beck Depression Inventory (BDI) 6. Hamilton Rating Scale for Depression (HAMD) 7. Montgomery-Asberg Depression Scale (MADRS) 8. Zung Self-rating Depression Scale (SDS) 9. Apathy scale (AS) 10. Mini-Mental State Examination (MMSE) 11. Frontal Assessment Battery (FAB) 12.Japanese version of Montreal Cognitive Assessment (MoCA-J) 13.Keio version Wisconsin card sorting test (KWCST) 14. other complications	—

Measure

Time frame

1.Unified Parkinoson's Disease Rating Scale (UPDRS) part I, II, IV 2.UPDRS-III (on/off stimulation, on/off medication) 3. Impedance 4.threshoulds for efficacy and side effect of DBS 5. Beck Depression Inventory (BDI) 6. Hamilton Rating Scale for Depression (HAMD) 7. Montgomery-Asberg Depression Scale (MADRS) 8. Zung Self-rating Depression Scale (SDS) 9. Apathy scale (AS) 10. Mini-Mental State Examination (MMSE) 11. Frontal Assessment Battery (FAB) 12.Japanese version of Montreal Cognitive Assessment (MoCA-J) 13.Keio version Wisconsin card sorting test (KWCST) 14. other complications

—

Countries

Japan

Contacts

Public ContactGenko Oyama

Juntendo University Department of Neurology

g_oyama@jutendo.ac.jp+81-3-3813-3111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026