The effect of single administration of alpha-glucosidase inhibitors or sitagliptin on glucose metabolism and gut-derived hormones

The effect of single administration of alpha-glucosidase inhibitors or sitagliptin on glucose metabolism and gut-derived hormones - The effect of single administration of alpha-glucosidase inhibitors or sitagliptin on glucose metabolism and gut-derived hormones

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000009981

Enrollment

Registered

2013-08-01

Start date

2010-04-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Type 2 diabetes

Interventions

Acarbose 100mg Migritol 50mg Sitaguliptin 50mg Control

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Out patient of type 2 diabetes without medication. HbA1c level is less than 9%.

Exclusion criteria

Exclusion criteria: Type 1 diabetes, malignancy, infection, or severe liver or renal dysfunction.

Design outcomes

Primary

Measure	Time frame
The changes of plasma glucose, insulin, GLP-1, GIP, glucagon, and ghrelin after meal tolerance test.	—

Countries

Japan

Contacts

Public ContactHiroaki Ueno

Faculty of Medicine, University of Miyazaki Neurology, Respirology, Endocrinology and Metabolism, Department of Internal Medicine

intron@med.miyazaki-u.ac.jp+81-985-85-2965

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026