healthy male and female
Conditions
Interventions
salazosulfapiridine, wash out, crucumin, salazosulfapiridine
Sponsors
Clinical Pharmacokinetics, Graduate School of Pharmaceutical Sciences, Kyushu University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: The investigators must ensure that all subjects being considered meet the ollowing inclusion criteria: 1) Japanese healthy male or female who is capable to understand and sign the informed consent 2) 20-45 years of age 3) BMI 17.6-26.4 4) good health as determined by physical examination, vital signs and laboratory tests.
Exclusion criteria
Exclusion criteria: The investigators must ensure that all subjects being considered meet the ollowing exclusion criteria or conditions: 1) history of allergy to any drugs 2) medical attention within 2 months prior to participation 3) donation of 200 mL or more of blood within 4 weeks prior to participation, or donation of component blood within 2 weeks prior to participation 4) donation of 400 mL or more of blood within 12 weeks prior to participation 5) recent (past 4 months) participation in other clinical trial for investigational new chemical entity 6) history of drug abuse 7) alcohol abuse.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| pharmacokinetics of salazosulfapiridine, blood miR-328 levels | — |
Countries
Japan
Contacts
Public ContactNoritomo Izumi
LTA Hakata Clinic
Outcome results
None listed