Influence of time of day on propofol dose for anesthesia induction

Influence of time of day on propofol dose for anesthesia induction - Chronopharmacology of propofol

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000009940

Enrollment

Registered

2013-02-06

Start date

2013-01-28

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

All 90 subjects were ASA physical status I or II, between the ages of 18 and 65 years, and were scheduled for elective procedures under general anesthesia

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Subjects whose ASA physical status I or II, and were scheduled for elective procedures under general anesthesia. Written informed consent will be obtained.

Exclusion criteria

Exclusion criteria: 1) Allergy to propofol and/or eggs 2) History of neuropsychiatric disorders 3) Taking mind-altering drugs 4) Obese patients whose Body Mass Index are more than 35 kg/m2 5) Hypertension, diabetes, endocrine diseases 6) Deafness

Design outcomes

Primary

Measure	Time frame
Total propofol induction dose required to achieve loss of consciousness (LOC) Time to LOC	—

Countries

Japan

Contacts

Public ContactShinju Obara

Fukushima Medical University Anesthesiology, School of Medicine

shinjn@fmu.ac.jp0245471111ext.2464

Outcome results