Relationship among intrarenal renin-angiotensin system activity, circadian variation of blood pressure and renal damage by salt laoding for chronic kidney disease patients

Relationship among intrarenal renin-angiotensin system activity, circadian variation of blood pressure and renal damage by salt laoding for chronic kidney disease patients - Relationship among intrarenal RAS activity, circadian variation of BP and renal damage by salt laoding for CKD patients

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000009938

Enrollment

Registered

2013-02-04

Start date

2013-02-04

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic kidney disease

Interventions

After admission for renal biopsy, salt diet of 10 g/day is fed for one week. Next day, blood pressure is measured every 30 minutes during 24 hours, blood is taken at 6 a.m. and 9 p.m., and urine is c

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: CKD patients that have stage 1 to 3 and urinary protein < 1.0 g/day, irrespective of causes

Exclusion criteria

Exclusion criteria: CKD patients that have stage 4 to 5 and/or urinary protein >= 1.0 g/day

Design outcomes

Primary

Measure	Time frame
Comparison of urinary sodium excretion, intrarenal RAS activity, renal damage and blood pressure between normal and low salt diets	—

Countries

Japan

Contacts

Public ContactNaro Ohashi

Hamamatsu University School of Medicine First Department of Medicine

ohashi-n@hama-med.ac.jp053-435-2261

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026