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Effects of droperidol on postoperative abnormal behaviors in children undergoing general anesthesia: Systematic review and meta-analysis of randomized controlled trials.

Effects of droperidol on postoperative abnormal behaviors in children undergoing general anesthesia: Systematic review and meta-analysis of randomized controlled trials. - Effects of droperidol on postoperative abnormal behaviors in children undergoing general anesthesia: Systematic review and meta-analysis of randomized controlled trials.

Status
Active, not recruiting
Phases
Unknown
Study type
Unknown
Source
JPRN
Registry ID
JPRN-UMIN000009900
Enrollment
Unknown
Registered
2013-02-01
Start date
2013-02-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

postoperative abnormal behaviors such as agitation or restless in children undergoing general anesthesia

Interventions

None listed

Sponsors

Department of Anesthesiology and Critical Care Medicine, Yokohama City University Graduate School of Medicine
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: All randomized controlled trials comparing droperidol with any comparator (i.e., placebo, any drugs, or no treatment) administered during or before general anesthesia in children are included in this study. Eligibility is not restricted by language, type of surgery, or anesthetic technique.

Exclusion criteria

Exclusion criteria: We exclude studies which did not report our primary or secondary outcomes (i.e., postoperative abnormal behaviors such as agitation or restless, extrapyramidal symptoms, or sedation). We exclude studies which did not compare droperidol with any comparator (e.g., droperidol and midazolam vs. fentanyl), whereas we include studies "droperidol and drug A vs. drug A" because we can count the study as "droperidol vs. placebo". We also exclude data from abstracts, posters, case reports, comments or letters to the editor, reviews, and animal studies.

Design outcomes

Primary

MeasureTime frame
The primary outcomes of this present meta-analysis are the incidence of postoperative abnormal behaviors such as agitation, restless, or extrapyramidal symptoms.

Secondary

MeasureTime frame
The secondary outcomes are the incidence of sedation.

Countries

Japan

Contacts

Public ContactTakahiro Mihara

Yokohama City University Graduate School of Medicine Department of Anesthesiology and Critical Care Medicine

miharaxxxtotoro@yaoo.co.jp045-711-2351

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026