A study about immunogenicity and safety of an additional varicella vaccination

A study about immunogenicity and safety of an additional varicella vaccination - A study about an additional varicella vaccination

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000009888

Enrollment

Registered

2013-01-28

Start date

2011-02-03

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

varicella

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Healthy children with an agreement of a parent on this study , who received varicella vaccine at the pediatric outpatient clinic of Konan Kosei Hospital in Japan between two years from Apr 2006 to Mar 2008

Exclusion criteria

Exclusion criteria: We exclude the subjects who had antibody to VZV before an initial varicella vaccination, the subjects who received an additional varicella vaccination because of lack of seroconversion, and the subjects who had a history of breakthrough varicella.

Design outcomes

Primary

Measure	Time frame
1) IAHA and gpELISA antibody positive rates and mean IAHA and gpELISA antibody titers before and 4-6 wks after an additional varicella vaccination. 2) Comparison of the mean antibody titers after an additional vaccination and that after initial vaccination. 3) Incidence of clinical reactions for 4 weeks after an additional varicella vaccination. 4) Comparison of the incidence of clinical reactions after an additional varicella vaccination and that after initial vaccination.	—

Measure

Time frame

1) IAHA and gpELISA antibody positive rates and mean IAHA and gpELISA antibody titers before and 4-6 wks after an additional varicella vaccination. 2) Comparison of the mean antibody titers after an additional vaccination and that after initial vaccination. 3) Incidence of clinical reactions for 4 weeks after an additional varicella vaccination. 4) Comparison of the incidence of clinical reactions after an additional varicella vaccination and that after initial vaccination.

—

Countries

Japan

Contacts

Public ContactNaoko Nishimura

Konan Kosei Hospital Department of Pediatrics

0587-51-3333

Outcome results