Adjustment of blood coagulation for cardiopulmonary bypass surgery: Optimal dosage of tranexamic acid using thromboelastometry

Adjustment of blood coagulation for cardiopulmonary bypass surgery: Optimal dosage of tranexamic acid using thromboelastometry - Optimal dosage of tranexamic acid for cardiopulmonary bypass surgery

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000009883

Enrollment

Registered

2013-01-28

Start date

2012-07-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

patients undergoig cardiac surgery with cardiopulmonary bypass

Interventions

loding dose of tranexamic acid 12.5mg/kg,contnuous dose 6.5mg/kg/hr, extracorporealcirculation circuit dose 1mg/kg loding dose of tranexamic acid 21mg/kg,contnuous dose 11mg/kg/hr, extracorporealcircu

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: patients undergoing cardiac surgery using extracorporeal circulation (a written informed consent was obtained from each participant),first coronary artery bypass grafting/mitral valve plasty/mitral valve replacement/aortic valve replacement

Exclusion criteria

Exclusion criteria: renal dysfunction

Design outcomes

Primary

Measure	Time frame
perioperative blood loss, perioperative fibrinolytic system, ICU stay, postoperative seizure	—

Countries

Japan

Contacts

Public ContactSungsam Cho

Nagasaki University Hospital Anesthesiology

chos@nagasaki-u.ac.jp095-819-7370

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026