Associations of changes in HbA1c, insulin sensitivity, abdominal fat and plasma fatty acid composition with changes in macronutrients, carbohdyrate sources and alcohol intake under a 6-month moderate low-carbohydrate diet in type 2 diabetes

Associations of changes in HbA1c, insulin sensitivity, abdominal fat and plasma fatty acid composition with changes in macronutrients, carbohydrate sources and alcohol intake under a 6-month moderate low-carbohydrate diet in type 2 diabetes - Associations of changes in HbA1c, insulin sensitivity and abdominal fat with changes in macronutrients, carbohydrate sources and alcohol intake under a moderate low-carbohydrate diet in type 2 diabetes

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000009866

Enrollment

240

Registered

2013-01-25

Start date

2013-01-04

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Type 2 diabetes

Interventions

A moderate-low carbohydrate diet(dietary %energy from carbohydrate ranged from 30 to 60%)

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients with type 2 diabetes not taking anti-diabetic patients

Exclusion criteria

Exclusion criteria: Patients with serum creatinine levels > 2.0 mg/dl, ketoacidosis, soft drink ketosis, severe heart failure, severe liver cirrhosis, cancer, insulin therapy and implementing a low-carbohydrate diet at baseline.

Design outcomes

Primary

Measure	Time frame
BMI, Hemoglobin A1c levels, plasma fatty composition, insulin sensitivity estimated by 75g-glucose tolerance test, abdominal fat measured by CT, macronutrients, carbohydrate sources, the type of protein, fat and alcohol by 3-day dietary records at baseline and after 6 months.	—

Secondary

Measure	Time frame
Blood pressure, serum lipid profiles, blood chemical examinations, CT values of liver and spleen, micronutrients and salt equivalents estimated by 3-day dietary records, doses of anti-diabetic drugs, lipid lowering drugs and anti-hypertensive drugs at baseline and after 6 months.	—

Countries

Japan

Contacts

Public ContactHajime Haimoto

Haimoto Clinic Department of Internal Medicine

haimoto@gol.com0568-85-0567

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026