Randomized controlled trial to evaluate the clinical efficacy of once- or twice-daily showering for prevention of atopic eczema exacerbation.

Randomized controlled trial to evaluate the clinical efficacy of once- or twice-daily showering for prevention of atopic eczema exacerbation. - Evaluation of once- or twice-daily showering on atopic eczema.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000009864

Enrollment

120

Registered

2013-01-28

Start date

2013-01-28

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Atopic eczema

Interventions

Once-daily showering Twice-daily showering

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Atopic eczema diagnosed with Hanifin & Rajka criteria. 2) Moderate or severe atopic eczema in the recent two years. 3) Applying topical corticosteroid every three or four days to keep good skin condition. 4) Mild eczema or cleared at registration. 5) Showering twice-daily. 6) Pruritus score is two points out of ten or less.

Exclusion criteria

Exclusion criteria: Taking oral corticosteroids and/or oral immunosuppressive agents.

Design outcomes

Primary

Measure	Time frame
1. The rate of patients without exacerbation. 2. Number of days until the first exacerbation.	—

Secondary

Measure	Time frame
1. Number of weeks with additional application of topical corticosteroid. 2. Caregiver's QOL. 3. Scoring atopic dermatitis. (SCORAD) 4. Patient oriented eczema measure. (POEM) 5. Pruritus and sleeplessness score. 6. Incidence of skin infection.	—

Countries

Japan

Contacts

Public ContactYukihiro Ohya

National Center for Child Health and Development Division of Allergy

ohya-y@ncchd.go.jp03-3416-0181

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026