Acute cystitis
Conditions
Interventions
sitafloxacin(200mg daily)
Sponsors
Jikei university katsushika medical center,Department of urology
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: (1)age,sex:20 years old or older,female (2)inclusion criteria 1)symptoms:miction pain ,urinary urgency, pollakisuria,lower abdominal pain,or sever of residual urine. 2)pyuria:white blood cells is 5/hpf or more in urinary sediment. 3)bacterial count:104 CFU/mL in catheterized urine or105 CFU/mL in midstream urine.
Exclusion criteria
Exclusion criteria: (1)Patient who has urinary catheter. (2)Patient who has urinary diversion. (3)Patient who has been administered other antibiotics and her symptom has been improved before starting administration of this study. (4)Patient administered sitafloxacin within a week before starting administration of this study. (5)Patient with severe infectious disease, who cannot be expected efficacy of oral antimicrobials therapy. (6)Patient with severe underlying disease or complications, who cannot be evaluated efficacy and safety of this study. (7)Patient with a history of allergies against fluoroquinolone. (8)Patient with severe cardiac or hepatic dysfunction. (9)Patient with moderate renal dysfunction (Criteria: Serum Creatinine >2mg/dL) (10)Patient with convulsive disorders like epilepsy or with a history of these deseases. (11)Pregnant women. (12)Patient disqualified as target by doctor.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Eradication of symptoms and causative organisms after administration of sitafloxacin. | — |
Countries
Japan
Outcome results
None listed