Cerebrovasucular Disease, Hypertension
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Outpatients to fulfill all the following condition can participate 1)Hypertension with cerebrovasucular disease 2)Under treatment with ARB is not telmisartan more than 3 months 3)Clinic BP:SBP>=140 and/or DBP>=90 4)40 years of age and more 5)Patients with informed consent of this study
Exclusion criteria
Exclusion criteria: 1)Secondary hypertension 2)Severe hypertension with SBP>=180mmHg and/or DBP>=110mmHg 3)Malignant hypertension 4)Severe heart failure (NYHA III-IV) 5)Myocardial Infarction, Coronary bypass surgery, and PTCA were performed within 6 months 6)Patients contraindicated for the use of ARBs 7)Serum creatinine >=2.1mg/dL 8)Untreated hyperuricemia or serum uric acid>8mg/dL 9)Diabetes patients under insulin treatment, or HbA1c>9.0% 10)Patients with hypoglycemia 11)Patients who are inadequate by determination of physicians in charge
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Central blood pressure | — |
Secondary
| Measure | Time frame |
|---|---|
| Clinic BP 24hr BP on ABPM IMT(Intra Media Dilation) FMD(Flow Mediated Dilation) Control rate of Clinic BP Control rate of ABPM | — |
Countries
Japan