Randomized controlled trial of febuxostat and allopurinol on chronic heart failure patients with hyperuricemia

Randomized controlled trial of febuxostat and allopurinol on chronic heart failure patients with hyperuricemia - Comparison of the effect of hyperuricemic drug on chronic heart failure patients

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000009817

Enrollment

500

Registered

2013-01-20

Start date

2012-12-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic heart failure with hyperuricemia

Interventions

Febuxostat:250 Period: 2012.12-2016.3 allopurinol:250 Period: 2012.12-2016.3

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1.Chronic heart failure patients with hyperuricemia 2.Stable outpatients (NYHA I-III)

Exclusion criteria

Exclusion criteria: 1.Acute heart failure patients or acute myocardial infarction patients 2.Patients with renal failure (over Cr 2.0 mg/dl) 3.Patients who had already anti-hyperuricemic drug 4.Patietns with hypersensitivity of study drug 5.Pregnant woman

Design outcomes

Primary

Measure	Time frame
Cardiac death and rehospitalization due to worsening heart failure	—

Countries

Japan

Contacts

Public ContactSatoshi Suzuki

Fukushima Medical University Department of Cardiovascular Medicine

ssatoshi@fmu.ac.jp024-547-1190

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026