The effect of intravitreal injection of bevacizumab after vitrectomy for proliferative diabetic retinopathy

The effect of intravitreal injection of bevacizumab after vitrectomy for proliferative diabetic retinopathy - The effect of intravitreal injection of bevacizumab after vitrectomy

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000009801

Enrollment

Registered

2013-04-01

Start date

2013-04-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

proliferative diabetic retinopathy

Interventions

The VEGF concentration in vitreous humor carries out intravitreal administration of AvastinOR by visitors to the case which was 1,000 pg(s)/ml. Under clean, one vial (100 mg/four ml) of AvastinOR is

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: It is a case which needs a first time operation at multiplication diabetic retinopathy.

Exclusion criteria

Exclusion criteria: It is IVB medication before an operation.

Design outcomes

Primary

Measure	Time frame
(1) Primary endpoint Frequency of postoperative vitreous body re-bleeding (2) Secondary endpoint A. Evaluation of the activity of the new blood vessel by the anterior ocular segment photograph and a fundus-of-the-eye photograph B. Evaluation of the activity of the new blood vessel by fluorescence fundus-of-the-eye imaging C. The improvement factor of eyesight D. The improvement factor of the thickness of the retina by an optical interference fault meter E. The improvement factor of intraocular pressure	—

Measure

Time frame

(1) Primary endpoint Frequency of postoperative vitreous body re-bleeding (2) Secondary endpoint A. Evaluation of the activity of the new blood vessel by the anterior ocular segment photograph and a fundus-of-the-eye photograph B. Evaluation of the activity of the new blood vessel by fluorescence fundus-of-the-eye imaging C. The improvement factor of eyesight D. The improvement factor of the thickness of the retina by an optical interference fault meter E. The improvement factor of intraocular pressure

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Countries

Japan

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026