schizophrenia
Conditions
Interventions
Cognitive training focused on working memory consisting of two 45 min computer sessions (computer soft) and a 45 min verbal session (group meeting) per week during 12 weeks
Cognitive training (NEAR) t
Sponsors
National Center Hospital, National Center of Neurology and Psychiatry
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Forty-five patients with schizophrenia according to the DSM-IV criteria recruited from outpatients and inpatients of National Center Hospital, National Center of Neurology and Psychiatry (NCNP). All patients were 20-60 years old and had the capacity to give written informed consent.
Exclusion criteria
Exclusion criteria: (1)Patients with the estimated IQ lower than 80 (by Japanese Adult Reading Test) (2)Patients with history of organic brain disorder, dementia, pervasive developmental disorder, or substance/alcohol dependence. (3)Patients with severe irritation that hindered them from being seated still during the experiment. (4)Patients for whom changes in medication were presumed to be necessary during the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Brain activation and behavioral parameters using new delayed response task focused on central executive system along with verbal N-back task and non-verbal N-back task PANSS BACS CSB JART-25 | — |
Secondary
| Measure | Time frame |
|---|---|
| UPSA-B SFS SLOF SF36 FEIT-J Hinting task SCSQ | — |
Countries
Japan
Contacts
Public ContactKazuyoshi Takeda
National Center Hospital, National Center of Neurology and Psychiatry Department of Psychiatry
Outcome results
None listed