GI epithelial lesions
Conditions
Interventions
Transvenous administration of 10% solution or topical application of 0.1% fluorescein solution will be performed for tissue visualization with CLE. Then, the studied sites will be biopsied and the spe
Sponsors
Department of Endoscopy The Jikei University School of Medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients with suspected digestive disease such as a gastric carcinoma, gastric adenoma, colon carcinoma, colon adenoma.
Exclusion criteria
Exclusion criteria: 1) Patients not indicated for normal endoscopy 2) History of allergy to fluorescein dye 3) Subjects with a severe comorbidity such as a diabetic disease, cardiovascular, neurologic dysfunction, cirrhosis of the liver, pheochromocytoma and pregnancy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The procedural success rate of the visualization of the structure. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1) Comparing CLE findings with normal endoscopic findings, magnifying-endoscopic findings and pathological findings 2) Differential diagnosis 3) Image quality assessment. The evaluation criteria are divided into three(poor, almost invisible tissue structure; mild, visible tissue structure with too dark vision; good, clearly visible tissue structure). 4) Adverse events | — |
Countries
Japan
Contacts
Public ContactMasakuni Kobayashi
The Jikei University School of Medicine Department of Endoscopy
Outcome results
None listed