A prospective multicenter study of EUS-guided choledochoduodenostomy for unresectable malignant biliary obstruction

A prospective multicenter study of EUS-guided choledochoduodenostomy for unresectable malignant biliary obstruction - EUS-guided choledochoduodenostomy for unresectable malignant biliary obstruction

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000009736

Enrollment

Registered

2013-01-09

Start date

2013-01-09

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients with unresectable malignant distal biliary obstruction

Interventions

EUS-guided choledochoduodenostomy

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. unresectable malignant distal biliary obstruction without prior drainage 2. Age >= 20 y.o. 3. Serum T.Bil >=2.0 mg/dL 4. ECOG Performance Status 0-2 5. Informed consent

Exclusion criteria

Exclusion criteria: 1. Ascites 2. Prior gastric surgery 3. Biliary obstruction within 2 cm from hepatic hilum 4. Failure to detect CBD on EUS 5. Patients on anticoagulant or antiplatelet medications 6. Coagulopathy (Platlet < 50,000 or PT-INR >=2) 7. Severe comorbidity 8. Failed informed consent 9. Patients considered to be inadequate for clinical trials

Design outcomes

Primary

Measure	Time frame
Techinical success	—

Secondary

Measure	Time frame
complications, stent patency	—

Countries

Japan

Contacts

Public ContactYousuke Nakai

The University of Tokyo Department of Gastroenterology, Graduate School of Medicine

ynakai-tky@umin.ac.jp03-3815-5411

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026