A physician-initiated translation of independent single-blind research for rice-based oral cholera vaccine, MucoRice-CTB in healthy volunteers

A physician-initiated translation of independent single-blind research for rice-based oral cholera vaccine, MucoRice-CTB in healthy volunteers - A physician-initiated independent translation research for MucoRice-CTB in healthy volunteers

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000009688

Enrollment

Registered

2013-01-22

Start date

2013-01-22

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cholera, Traveler&#39

Interventions

Test group(N=10) MucoRice-CTB (rice powder 750mg containing 1mg of CTB) Control group(N=10) Wild &amp

#8211

type rice (rice powder 750mg)

Eligibility

Sex/Gender

Male

Inclusion criteria

Inclusion criteria: Healthy male Age between 20 to 40 Negative test for anti-CT fecal IgA No severe hepatological, renal or hematological disorder No severe heart disease No medications Able and willing to give valid written informed consent

Exclusion criteria

Exclusion criteria: Rice allergy Past history of cholera or traveler's diarrhea Severe constipation Decision of unsuitableness by principal investigator

Design outcomes

Primary

Measure	Time frame
(1)CTB-specific serum IgG/IgA and CTB-specific fecal IgA immune responses (2)Safety issue: Rice-specific serum IgE immune response	—

Countries

Japan

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026