Constipation with breast cancer therapy
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: all the following conditions (1)Admit into the Kyoto University hospital for breast cancer treatment and receiving chemotherapy (2)Control emesis by the 5-HT3 receptor antagonist which include Ondansetron, Granisetron, Tropisetron, Palonosetron, before chemotherapy. (3)Performance Status 0 or 1 (4)able to defecate with normal digestive organ and trunk function (5)Signed informed consent for this study
Exclusion criteria
Exclusion criteria: (1)Difficult to accept the researcher by mental disorder, cognitive impairment or physical disability (2)Constipation before chemotherapy; higher than CTCAEv4.0 Grade2 (Persistent symptoms with regular use of axatives or enemas; limiting instrumental ADL) (3)Pregnant (4)Have difficulty in active exercise in physician judgement (5)Inappropriate for this study in physician judgement (5)In the chemotherapy term, it is necessary to continue aperient or supplement except our prescription in physician judgement
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Constipation (Score of Constipation assessment scale) | — |
Secondary
| Measure | Time frame |
|---|---|
| defecation use of laxative QOL mood and emotional state sleep activity rhythm Action | — |
Countries
Japan
Contacts
Kyoto university graduate school of medicine Clinical Cognitive Neuroscience