Effect of cardiac resynchronization therapy on phasic coronary flow pattern and microvascular resistance in patients with non-ischemic cardiomyopathy

Effect of cardiac resynchronization therapy on phasic coronary flow pattern and microvascular resistance in patients with non-ischemic cardiomyopathy - Effect of cardiac resynchronization therapy on coronary flow

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000009669

Enrollment

Registered

2013-01-01

Start date

2009-04-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Non-ischemic cardiomyopathy

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: The indications for CRT were severe HF (New York Heart Association [NYHA] functional class III or IV) despite optimal medical therapy, left ventricular ejection fraction (LVEF) &#8804; 35%, and QRS duration &#8805; 130 milliseconds (ms). Patients were included in this study, that met the following criteria: (1) non-ischemic cardiomyopathy assessed by coronary angiography, (2) sinus rhythm, (3) complete left bundle branch block (LBBB) or complete atrioventricular block (CAVB) , (4) implantation of first CRT device, including upgrade

Exclusion criteria

Exclusion criteria: Ischemic cardiomyopathy, decompensated HF, and significant renal dysfunction (serum creatinine &#8805; 2.0mg/dL) at 1week after CRT

Design outcomes

Primary

Measure	Time frame
Average peak velocity, phasic coronary flow parameters, coronary flow reserve, hyperemic microvascular resistance index	—

Countries

Japan

Outcome results