Assessment of the Benefits of the Addition of Botulinum Toxin A to a Repetitive Facilitative Exercise Program for the Upper Paretic Extremity in Chronic Stroke: A Randomized Controlled Study.

Assessment of the Benefits of the Addition of Botulinum Toxin A to a Repetitive Facilitative Exercise Program for the Upper Paretic Extremity in Chronic Stroke: A Randomized Controlled Study. - Assessment of the Benefits of the Addition of Botulinum Toxin A to a Repetitive Facilitative Exercise Program for the Upper Paretic Extremity in Chronic Stroke: A Randomized Controlled Study.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000009640

Enrollment

Registered

2012-12-26

Start date

2012-11-30

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Stroke

Interventions

The combination group of Botox injection and the Repetitive Facilitative Exercise Program Control group of only the Repetitive Facilitative Exercise Program

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Poststroke patients hospitalized for rehabilitation 2) Obtained informed consent 3) Patients are in the post-stroke period over six month following onset. 4) History of a single stroke only

Exclusion criteria

Exclusion criteria: 1) Refuse the Botox injection 2) Severe higher brain dysfunction, Severe dementia, Loss of consciousness 3) Active physical and psychological disorders

Design outcomes

Primary

Measure	Time frame
Fugl-Myer Assessment (FMA)	—

Secondary

Measure	Time frame
Modified Ashworth Scale (MAS), Action Research Arm Test (ARAT), Simple Test for Evaluating Hand Function (STEF), 9 Hole Peg Test (9-HPT), Box and Block test (BBT), Functional Independence Measure (FIM), Visual Analogue Scale (VAS), Goal Attainment Scaling (GAS)	—

Countries

Japan

Contacts

Public ContactAkihiko Hokazono

Kagoshima University Graduate School of Medical and Dental Sciences Department of Rehabilitation and Physical Medicine

aki88@m2.kufm.kagoshima-u.ac.jp0995-78-2538

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026