Clinical study for reducing the risk of progress of idiopathic osteonecrosis of the femoral head (ION) by teriparatide treatment

Clinical study for reducing the risk of progress of idiopathic osteonecrosis of the femoral head (ION) by teriparatide treatment - Risk reduction of progress of ION

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000009610

Enrollment

Registered

2012-12-26

Start date

2012-12-26

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

idiopathic osteonecrosis of the femoral head

Interventions

Teriparatide Acetate Normal treatment

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Inclusion criteria: Patients with ION over 20 years old Diagnosis of ION: Two or more items that meet the following; 1.Femoral head collapse or subchondral fracture in femoral head observed by X-ray film 2.Cystic and sclerotic changes in femoral head by X-ray film 3.Cold in hot image in femoral head by scintigraphy 4.Bone necrosis with repair reaction by bone biopsy 5.Band pattern in femoral head by MRI

Exclusion criteria

Exclusion criteria: 1.Patients with contraindication of teriparatide 2.Patient who was not obtained informed consent 3.Hips already receiving osteotomy or hip arthroplasty by ION 4.Patients with severe renal dysfunction, hepatic dysfunction, and cardiac dysfunction 5.Hips with osteoarthritis changes

Design outcomes

Primary

Measure	Time frame
Incidence of femoral head collapse by X-ray film Rate of osteotomy or hip arthroplasty	—

Countries

Japan

Contacts

Public ContactHiromasa Tanino

Asahikawa Medical University Department of Orthopaedic Surgery

taninohiromasa@hotmail.com0166652111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026