heart failure
Conditions
Interventions
tolvaptan group
conventional treatment group
Sponsors
University of Tokyo Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) patients who was diagnosed with Frammingham criteria 2) in-hospital patients 3) patients who had a previous history of in-hospital treatment due to heart failure 4) NYHA III or IV 5) patients using over 60mg/day of fulosemide 6) patients with physical symptom due to heart failure 7) each gender is permitted 8) patients over 20 year old 9) patients able to consent 10) patients who consented himself
Exclusion criteria
Exclusion criteria: 1) serum sodium concentration over 145mEq/L 2) patients who were administered tolvaptan before admission 3) patients who had received mechanical devices 4) patients with acute coronary syndrome 5) patients with future surgical procedure 6) patients with anuria 7) patients unable to drink 8) patients unable to take medicine orally 9) patients with urine osmolality under 350 mOsm/L
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| QOL score (Minnesota Living With Heart Failure Questionnaire) | — |
Countries
Japan
Contacts
Public ContactKoichiro Kinugawa
University of Tokyo Hospital Department of Therapeutic Strategy
Outcome results
None listed