Gastrointestinal stromal tumor
Conditions
Interventions
None listed
Sponsors
The Research Group for Rare Neoplasms of Japan
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) The diagnosis of GIST is confirmed by KIT-positive of resected specimen or acquiring of genetic mutations with c-kit and PDGFRA 2) The subject is classified as high risk based on the modified-Fletcher Classification (Joensuu) 3) In initial GIST, a complete gross resection had been conducted and the resection is within 3 years prior to registration (if recurrence is found at the time, the registration shall be permitted when above condition is met.) 4) Over 20 years old 5) Patients are able to provide written informed consent, if the patient died at the time of registration, a consent must be obtained from the legal representative of the person (Unless it has been six months or more after the surgery) 6) After the surgery, a periodic imaging test (every 6 months) has been conducted to examine possibility of recurrence
Exclusion criteria
Exclusion criteria: 1) In case the patient has other serious illnesses other than GIST (other cancer, cardiovascular disease, brain disease, and hepatorenal diseases etc). 2) Resection of metastases/ disseminated lesion was concluded in initial GIST, a complete gross resection 3) In case the physician determines that participation in the study is not appropriate.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Recurrence-free survival | — |
Secondary
| Measure | Time frame |
|---|---|
| -Overall survival -Occurrence and severity of adverse events -Completion of treatment | — |
Countries
Japan
Contacts
Public ContactSatoshi Nakagawa
Translational Research Center for Medical Innovation None
Outcome results
None listed