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Cerebral blood flow in hypothyroidism: ASL(Arterial Spin Labeling) study

Cerebral blood flow in hypothyroidism: ASL(Arterial Spin Labeling) study - CBF in hypothyroidism

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
JPRN
Registry ID
JPRN-UMIN000009486
Enrollment
70
Registered
2012-12-05
Start date
2012-11-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

transient hypothyroidism in induced by post-thyroidectomy

Interventions

None listed

Sponsors

Institute of Biomedical and Health Sciences, Hiroshima University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients:1.After thyroidectomy and before I-131 therapy. 2. People twenty years old and over at the time of the consent. 3. People who see a doctor regularly in Hiroshima University Hospital after I-131 therapy. 4. People who can consent to this study in writing. Control: 1. People who don't have any metal disorders. 2. People who don't have thyroidal disorders. 3. People who don't have any other seriously ill. 4. People who can consent to this study in writing.

Exclusion criteria

Exclusion criteria: 1. Contraindication to MRI(cardiac pacemaker; cochlear implantation device; defibrillator; neurostimulator; bone growth stimulation device; infusion pump; deep brain stimulation; cervical artery crump(Poppen-Blaylock); chip of ferromagnetic substance in eyeball, brain, internal organs, lung, mediastinum; intraaortic filter, intravascular coil or stent within 2 months) 2. People who were unsuitable for this study.

Design outcomes

Primary

MeasureTime frame
A comparison of rCBF of the patients and control groups.

Secondary

MeasureTime frame
1. The effects of thyroxine treatment on rCBF changes 2. The association between Hamilton Rating Scale for Depression(HAMD)/Beck Depression Index(BDI) and rCBF. 3. The association between FT3/FT4 and rCBF.

Countries

Japan

Contacts

Public ContactYoko Kaichi

Graduate School of Biomedical and Health Sciences, Hiroshima University Diagnostic Radiology

kaichi@hiroshima-u.ac.jp082-257-5257

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026