Cross-over study of eating snacks at different timing on glycemic excursions assessed by continuous glucose monitoring system (CGMS) in patients with and without type 2 diabetes

Cross-over study of eating snacks at different timing on glycemic excursions assessed by continuous glucose monitoring system (CGMS) in patients with and without type 2 diabetes - Cross-over study of eating snacks at different timing on glycemic excursions assessed by CGMS

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000009465

Enrollment

Registered

2012-12-03

Start date

2012-12-17

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Type 2 diabetes

Interventions

All participants are assigned to perform CGM for 6 days by eating snacks after lunch or dinner or between lunch and dinner in a randomized cross-over design. At 12:00 of the first day, each participan

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Consecutive adult patients with type 2 diabetes are recruited among outpatients regularly attending diabetes clinic, Kajiyama Clinic located in Kyoto, Japan. All patients had type 2 diabetes as defined by Word Health Organization criteria, and HbA1c less than 9%. Healthy adults without type 2 diabetes are recruited.

Exclusion criteria

Exclusion criteria: Patients who have liver disease, any life-threatening disease, severe complications of diabetes, nephropathy, history of cerebral or myocardial infarction, and treatment with steroidal anti-inflammatory drugs, and drug or alcohol abuse are excluded.

Design outcomes

Primary

Measure	Time frame
Daily glucose excursions; mean glucose, glucose standard diviaion, mean amplitude of glycemic excursions (MAGE), largest amplitude of glycemic excursions (LAGE).	—

Secondary

Measure	Time frame
Postaprandial plasma glucose, incremental area under the curve (IAUC)	—

Countries

Japan

Contacts

Public ContactSaeko Imai

Kyoto Women's University Department of Food and Nutrition, Faculty of Home Economics

imais@kyoto-wu.ac.jp075-531-7128

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026