Which is effective and safe for persistent pulmonary hypertension after pulmonary endarterectomy, NO or Flolan?

Which is effective and safe for persistent pulmonary hypertension after pulmonary endarterectomy, NO or Flolan? - Which is effective and safe for persistent pulmonary hypertension after pulmonary endarterectomy, NO or Flolan?

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000009460

Enrollment

Registered

2013-01-01

Start date

2012-12-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

persistent pulmonary hypertension after pulmonary endarterectomy

Interventions

NO inhalation therapy will begin, if the patient develops pulmonary hypertension (mean pulmonary artery pressure above 25 mmHg) after separation from cardiopulmonary bypass. NO therpy will stop, if pu

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: the patient who develops pulmonary hypertension (mean pulmonary artery pressure above 25 mmHg) after separation from cardiopulmonary bypass.

Exclusion criteria

Exclusion criteria: patients with bleeding complication will be excluded.

Design outcomes

Primary

Measure	Time frame
effectiveness of lowering pulmonary artery pressure	—

Countries

Japan

Contacts

Public ContactKeiichi Ishida

Chiba University Hospital Dept.of Cardiovascular Surgery

keiichi-ishida@pro.odn.ne.jp0432262733

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026