A randomized, double-blind, sham-controlled study of static electric field therapy by high voltage alternating current for active rheumatoid arthritis

A randomized, double-blind, sham-controlled study of static electric field therapy by high voltage alternating current for active rheumatoid arthritis - EF-HVAC-RA

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000009442

Enrollment

Registered

2012-11-30

Start date

2012-12-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

a randomized, double-blinded, sham-controlled trial

Interventions

EF-HVAC therapy group: Patients were exposed to EF-HVAC with a high voltage value for 20 min a day until 2 weeks, and then were treated 60 min a day to 12 week using a Legacis Plus System (COCOROKA Lt

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Selected patients presented RA and fulfilled the ACR 1987 criteria for diagnosis of RA.

Exclusion criteria

Exclusion criteria: Patients were excluded from the study if they received biological therapies for RA, were diagnosed with another inflammatory disease or experienced uncontrolled or clinically significant systemic diseases other than RA.

Design outcomes

Primary

Measure	Time frame
the improvement of the activity of subjects by 28-joints disease activity score based on CRP (DAS28-CRP)	—

Secondary

Measure	Time frame
VAS for pain, swollen joint score, tender joint score, modified health assessment questionnaire, and changes in laboratory measures of biomarkers	—

Countries

Japan

Contacts

Public ContactYuji Naito

Kyoto Prefectural University of Medicine Gastroenterology and Hepatology

ynaito@koto.kpu-m.ac.jp+81752515519

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026