Effect of Diquafosol Sodium Eye Drops on Tear Film Stability

Effect of Diquafosol Sodium Eye Drops on Tear Film Stability - Effect of Diquafosol Sodium Eye Drops on Tear Film Stability

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000009438

Enrollment

Registered

2012-12-01

Start date

2011-06-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

unstable tear film type of dry eye disease

Interventions

diquafosol sodium eye drop

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) presence of DED symptoms 2) Schirmers value more than 5 mm 3) BUT equal or less than 5 seconds 4) fluorescein score equal or less than 3 points (9 points maximum).

Exclusion criteria

Exclusion criteria: Eyes with contact lens wearing, active ocular surface disorders other than DED, history of ocular surgeries, presence of punctual plugs, meibomian gland dysfunction with more than moderate degree of severity, and receiving eye drops other than artificial tears or hyaluronic acid were excluded.

Design outcomes

Primary

Measure	Time frame
tear film break-up time, tear secretion, ocular surface damage, tear film stability, subjective symptom	—

Countries

Japan

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026