Intraocular Concentrations of Cytokines and Chemokines in Rhegmatogenous Retinal Detachment and the Effect of Intravitreal Triamcinolone Acetonide

Intraocular Concentrations of Cytokines and Chemokines in Rhegmatogenous Retinal Detachment and the Effect of Intravitreal Triamcinolone Acetonide - Intraocular Concentrations of Cytokines and Chemokines in Rhegmatogenous Retinal Detachment and the Effect of Intravitreal Triamcinolone Acetonide

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000009418

Enrollment

100

Registered

2012-11-28

Start date

2007-02-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Rhegmatogenous Retinal Detachment

Interventions

Intravitreal injection of 4 mg triamcinolone acetonide 1 day before 25 gauge vitrectomy.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: The inclusion criterion was clinically detectable rhegmatogenous retinal detachment.

Exclusion criteria

Exclusion criteria: The exclusion criteria were prior vitreous surgery or intravitreal injection of triamcinolone acetonide, intravitreal anti-vascular endothelial growth factor, ocular inflammation, and vitreoretinal or optic nerve diseases.

Design outcomes

Primary

Measure	Time frame
The concentrations of 15 soluble factors (three cytokines, seven chemokines, and five growth factors) were determined before IVTA and 1 day after intravitreal injection of triamcinolone acetonide. The association with clinical findings including macular status and visual acuity was then analyzed.	—

Countries

Japan

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026